Many conservation initiatives call for ‘transformative change’ to counter biodiversity loss, climate change, and injustice. The term connotes fundamental, broad, and durable changes to human relationships with nature. However, if oversimplified or overcomplicated, or not focused enough on power and the political action necessary for change, associated initiatives can perpetuate or exacerbate existing crises. This article aims to help practitioners deliberately catalyze and steer transformation processes. It provides a theoretically and practically grounded definition of ‘transformative conservation’, along with six strategic, interlocking recommendations. These cover systems pedagogy, political mobilization, inner transformation, as well as planning, action, and continual adjustment.